Ulcerative colitis (UC) is a chronic non-specific inflammation that mainly affects the mucosa of the rectum and colon, with abdominal pain, diarrhea, mucus and bloody stools as the main clinical manifestations. Establishing an animal model similar to human UC has important application value in studying the pathogenesis, progression, and clinical treatment of UC.

Ulcerative colitis rat model

潰瘍性結腸炎小鼠模型 

Observation indicators

Weight loss, loose stools accompanied by bloody stools, significantly increased intestinal wall thickness, and decreased epithelial goblet cells.

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